Ibrahim Önal Kimdir

BACKGROUND: The aim was to evaluate the epidemiological, clinical, laboratory, and radiologic data of children with SARS-CoV-2 positivity by polymerase chain reaction (PCR) together with treatment strategies and clinical outcomes and to evaluate cases of multisystem inflammatory syndrome in children (MIS-C) in this population. METHODS: This was a multicenter retrospective observational cohort study performed in the pediatric emergency departments of 19 tertiary hospitals. From March 11, , to May 31, , children who were diagnosed with confirmed nasopharyngeal/tracheal specimen SARS-CoV-2 PCR positivity or positivity for serum-specific antibodies against SARS-CoV-2 were included. Demographics, presence of chronic illness, symptoms, history of contact with SARS-CoV-2 PCR-positive individuals, laboratory and radiologic investigations, clinical severity, hospital admissions, and prognosis were recorded. RESULTS: A total of cases were included. While (%) cases resulted in a diagnosis of SARS-CoV-2 with PCR positivity, 87 (%) patients were diagnosed with MIS-C. Among SARS-CoV-2 PCR-positive patients, % were male and % had chronic illnesses. The median age was years (IQR: ) and (%) patients were aged

(1) Background: We aimed to describe the clinical features and outcomes of coronavirus disease (COVID) in children and late adolescents with inflammatory rheumatic diseases (IRD) and to measure their severity risks by comparing them with healthy children. (2) Methods: Among children and late adolescents found to be severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) positive via polymerase chain reaction (PCR) test, IRD patients with an at least six-months follow-up duration, and healthy children were included in the study. Data were obtained retrospectively. (3) Results: A total of ( (%) females) (healthy children: , IRD patients: ) subjects were included in the study. While of (%) experienced COVIDrelated symptoms, only 21 (%) required hospitalization with a median duration of 5 () days. Fever, dry cough, and fatigue were the most common symptoms. None of evaluated subjects died, and all recovered without any significant sequelae. The presence of any IRD was found to increase the risk of both hospitalization (OR: ; 95% CI: ) and symptomatic infection (OR: ; 95% CI: ). Furthermore, increasing age was significantly associated with symptomatic infection (OR: ; 95% CI: ). (4) Conclusions: Our study emphasizes that pediatric rheumatologists should monitor their patients closely for relatively poor COVID outcomes.