Bozyaka Hastanesi Genel Cerrahi

RETROSPECTIVE EVALUATION OF THE DIAGNOSIS AND TREATMENT OF THE GALL BLADDER CANCER

Introduction: Gall bladder cancer is a rare disease with poor prognosis and usually diagnosed at the late stages because sings and smptoms mimic other benign disorders of gall bladder. Incidence rises in elderly and other accompanying gall bladder pathologies make diagnosis confusions. Due to rareness of the disease there is no sufficient data in the literature. We examine the probable difficulties during the diagnosis and treatment of the disease. Material and Methods: Gall bladder cancer patients admitted to Izmir Bozyaka Training and Education Hospital between February and June were retrospectively examined based on demographic features, symptoms, coexistant diseases, diagnotic methods, preop diagnosis, surgical interventions, disease stages, histopathologic diagnosis, morbidity, mortality, follow-up and survival results. Results: Among 12 cholecystectomies in between the time interval mentioned above, 80 (0,6%9 gall bladder cancer had been diagnosed. There were 58(72%) female and 22(28%) male with overall mean age of 65(). Mostly abounded symptoms in decreasing order were abdominal pain (97%), jaundice (31%), nausea and vomitting (27%). All patients were undergone routine abdominal ultrasonographic evaluation and those revealed tumoral lesion at the gall bladder localisation were further examined with abdominal CT and/or MR/MRCP. Diagnosis of gall bladder cancer could be done preoperatively in 43(53,7%) cases and 8(22,5%) were diagnosed intraoperatively. Remaining 19 (23,7%) cases were diagnosed histopathologically after regular cholecystectomy. All the cases with gall bladder cancer were undergone laparotomy and 7(8,7%) cases with stage I; 16(20%) cases with stage II; 30(37,5%) cases with stageIII; 27(33,7%) with stage IV. Surgical interventions were cholecystectomy; cholecystectomy with different kinds of partial liver resections; cholecystectomy and biliary drainage procedures; partial cholecsytectomy or incisional biopsy. Adenocarcinoma was dominating histopathological diagnosis with 69(86,2%) cases however 5(6,2%) adenosquamous cancer, 5(6,2%) indiffent carconoma, 1 (1,2%) squamous carcinoma cases were diagnosed so for. The number of patients reached on the phone after discharge were Of them 13 were dead after average of 16,8() months and 9 patients were still alive for average of 48() months. Conclusion: Gall bladder cancer differantial diagnosis should be kept in mind due to presenting similar signs and symptoms of benign pathologies. Despite of the developments in diagnosis and agressive treatment modalities, gall bladder cancer is still a complex disorder with short survival and poor prognosis.

Konular:

Genel Cerrahi

Bay, Meslekte 4 yıl

Yiğit Kaan Şen Hakkında

Yiğit Kaan Şen, Genel Cerrahi uzmanı olarak İzmir Karabağlar ilçesinde İzmir Bozyaka Eğitim ve Araştırma Hastanesi isimli sağlık kuruluşunda görev yapmaktadır.

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Tıp Fakültesi: Maltepe Üniversitesi,

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