Mustafa Aydın Erzurum

ABSTRACT

Calf diarrheais the most common diseaseaffecting calves in the neonatal period resulting in economic losses. Although predisposing factorsplaya rolein the etiologyof the disease, in most cases, different pathogens are involved in the development of the infection. In this study, hemogram data, glutathioneand malondialdehydelevels were examined to determine lipid peroxidationand glutathionelevels in E. coli- and coronavirus-infected calves. Serum amyloid Aand calprotectinlevels were also analyzed to determine inflammatory status. The study included a total of 45 femaleMontofon calves aged0-1 week, including the E. coli group (15 calves), the coronavirusgroup (15 calves), and the control group(15 calves). Analysisrevealed that total leukocyte, neutrophil, lymphocyte, malondialdehyde, serum amyloid A, and calprotectinlevels increased in the coronavirus-infected calves compared with the E. coli group and the control group. In contrast, the levels of glutathione, one of the antioxidantmarkers, decreased. In conclusion, the main findings related to the determinationof inflammationand oxidative status were characterized by the presence of E. coli and coronavirusdiarrhea, and it is suggested that futurestudies may be guided by the fact that inflammatory conditions are higher in viral diseasethan in bacterial infection.