Goz Olcumundeki Degerler

Abstract :

Purpose: To compare the optical coherence tomography (OCT) measurements of retinal nerve fiber layer (RNFL) and ganglion cells complex (GCC) thickness in primary open-angle glaucoma patients and normal patients. Material and Method: eyes of subjects were enrolled in the study: 86 glaucoma patients and 51 normal subjects as a control group. RNFL and GCC were measured by OCT. The average values of GCC and RNFL for each eye, the superior and inferior half measurements and the signal strength indicator (SSI) results were recorded. Results were statistically evaluated by correlation among the glaucoma patients and comparison between the normal and glaucoma groups. Results: There was no significant difference between the groups for age and gender distributions. The mean RNFL and GCC measurements were [+ or -] [micro]m in glaucoma patients and [+ or -] [micro]m in normal subjects. Superior half measurements were [+ or -] [micro]m in glaucoma patients and [+ or -] [micro]m in normal subjects. Inferior half measurements were [+ or -] [micro]m in glaucoma patients and [+ or -] [micro]m in normal subjects. Both GCC and RNFL averages and superior and inferior measurements were found statistically significantly lower in glaucoma group. SSI results were also statistically significantly lower in the glaucoma group. SSI of RNFL results were statistically significantly lower compared to SSI of GCC. Discussion: The measurement of GCC by OCT was found as remarkable as the measurement of RNFL in distinguishing glaucoma patients from the normal subjects. (Turk J Ophthalmol ; ) Key Words: Glaucoma, optical coherence tomography, retinal nerve fiber layer, ganglion cells complex Amac: Primer acik acili glokomlu olgularda Optik Koherens Tomografi (OKT) ile olculen retina sinir lifi tabakasi ve gangliyon hucre kompleksinin kalinliklarinin normal olgular ile karsilastirilmasi. Gerec ve Yontem: Calismaya 86'si glokom 51'i normal olmak uzere olgunun gozu alindi. OKT ile retina sinir lifi tabakasi (RSLT) ve gangliyon hucre kompleksi (GHK) olcumleri yapildi. Her goz icin RSLT ve GHK ortalama degeri, alt ve ust yarilarin olcumu ile olcum sirasinda alet tarafindan verilen Sinyal gucu gostergesi (SGG) sonuclari kaydedildi. Sonuclar, glokom hastalarinin kendi aralarinda korelasyonu ve kontrol grubu ile karsilastirilmasi acisindan istatistiksel olarak degerlendirildi. Sonuclar: Her iki olgu grubu arasinda yas ve cinsiyet oranlari acisindan anlamli fark bulunmadi. RSLT ve GHK ortalama degerleri glokomlu ve normal olgularda sirasiyla 97,03[+ or -]13,85 [micro]m, ,48[+ or -]9,00 [micro]m; ust yari olcumleri yine sirasiyla 95,83[+ or -]13,71 [micro]m, ,49[+ or -]11,14 [micro]m; alt yari olcumleri ise 98,44[+ or -]15,63 [micro]m, ,50[+ or -]9,25 Im olarak saptandi. Tum degerler glokom olgularinda kontrol grubuna gore istatiksel olarak anlamli duzeyde dusuk bulundu. SGG sonuclari degerlendirildiginde ise yine glokom olgularinda kontrol grubuna gore istatiksel olarak anlamli duzeyde dusuk bulundu. RSLT SGG sonuclari, GHK SGG sonuclari ile karsilastirildiginda ise RSLT sonuclari GHK sonuclarina gore istatiksel olarak anlamli duzeyde dusuk bulundu. Tartisma: Glokom hastalarinin tani ve izleminde RSLT kadar GHK olcumunun de onemli oldugu dikkat cekici olmustur. (Turk J Ophthalmol ; ) Anahtar Kelimeler: Glokom, optik koherens tomografi, retina sinir lifi tabakasi, ganglion hucre kompleksi